Mite Avenge is non-toxic even if your dog licks it during or after application. It was formulated to be safe for the full range of dogs who develop mange:
- Small and toy breeds
- Senior dogs
- Dogs with MDR1 gene mutations (including Collies, Shelties, Australian Shepherds, and related breeds)
- Dogs who have had adverse reactions to chemical mange treatments
MDR1 (Multi-Drug Resistance 1) is a genetic mutation that prevents the blood-brain barrier from filtering out certain drugs, making common parasite treatments potentially fatal in affected breeds. Because Mite Avenge contains no chemical pesticides, it is safe for dogs with the MDR1 gene mutation. For more detailed information about the MDR1 Gene Mutation visit the Washington State, College of Veterinary Medicine.
Bottom line: If your dog is a sensitive breed, elderly, or has had a bad reaction to chemical treatments, Mite Avenge is formulated with them in mind.




